ea0070ep461 | Thyroid | ECE2020
Maria Paragliola Rosa
, Corsello Andrea
, Papi Giampaolo
, Melfa Eleonora
, Urbani Andrea
, Pontecorvi Alfredo
, Carrozza Cinzia
, Maria Corsello Salvatore
Background: Immune checkpoint inhibitors (ICI), anticancer therapy blocking specific molecules expressed in tumor microenvironment, are associated to several endocrine side effects. In particular, the use of PD-1/PD-L1 inhibitors is related to a higher incidence of thyroid dysfunction. The most frequent form of thyrotoxicosis is a destructive thyroiditis, which can evolve into hypothyroidism.Patient findings:We report the case of an 85 years-old patient,...